Podofilox Product Description
Podofilox is a brand name of podophyllotoxin. This remedy is of the vegetable origin which is got from the essence of podophyllum roots. The essences of podophyllum roots have been used for a long time in the folk medicine as sedative, emetic and vermicidal drugs. However, doctors have found out that they have cytostatic activity and block mitosis on the stage of metaphase.
Podofilox has an antitumoral, cytostatic, and amyctic action. It reduces the intensity of the inflammatory reactions and causes necrosis of the pointed condyloma.
The mechanism of the removal of the pointed condyloma is explained by the amyctic and mummifying action. Penetrating into condyloma the drug starts its action at once. It burns out the benign neoplasms from the inside that is why the pointed condyloma is gradually mummified and removed from the skin.
The drawback of Podofilox may be considered the absence of the healing effect. After the removal of the pointed condyloma from the skin there is a probability that verruga may appear. It is explained that despite the fact that Podofilox completely cleans the skin it does not cure the patient of HPV – Human Papillomavirus.
This virus may be in the cells of the human for a long time and in some cases it may cause the appearance of the pointed condyloma again.
In order to avoid the appearance of verruga it is necessary to stick to hygiene of the genitals, avoid promiscuous sexual contacts and have examinations of the doctor urologist/venerologist from time to time
Directions for the use
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Podofilox gel is used as an external treatment of the pointed genital condyloma.
For other forms of verruga and papilloma this drug may be also used but only after studying the neoplasms by the doctor.
Dosage and way of use
- Podofilox gel is easy to use. It is applied externally to each condyloma separatedly.
- The drug should reach only condyloma because if the drug reaches the healthy parts of the skin or mucous, it may lead to severe irritation.
- After the application the place of the solution application should be dried in order to avoid the irritation of the healthy skin contacting the condyloma.
- Podofilox should be applied every day once a day within 3 weeks.
- In case of the appearance of the side reactions and severe irritatio of the skin the schedule of the treatment may be changed: Podofilox is applied 2 times a day within 3 days, and then it is needed to have a break for 4 days. Then the treatment is restored according to such scheme within 3-4 weeks with breaks of a week's duration.
Precautions
- The clinical studies have shown that the higher concentration of the drug is needed for the pointed condyloma on the male penis and in the area of pubis. Applying Podofilox to the female genitals and area of anus lower concentration is needed because the tissue is more sensitive there and the risk of the appearance of the side reactions is higher.
- It is necessary to avoid sexual intercourses during the treatment.
- Pregnant women and also patients with the individual intolerance of podophyllotoxin are not recommended to use Podofilox.
Possible Side effects
The external use of Podofilox does not mean dangerous side effects. Oftentimes, the patient faces such reactions as: irritation of the skin, redness, itching, painful sensations, light edema (applying the drug to preputium).
The side effects may appear not at once but the next day. In case of the severe side reactions it is possible to use the anti-inflammatory drugs of the external use (to reduce the edema), or use the protective creams, mineral butter which are applied to the healthy skin before the use of Podofilox (such way will reduce the irritation and redness of the skin).
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Buy Podofilox Online (Topical solution)
Podofilox is available as Podowarts 20% solution.